TGFB1 and cirrhosis of liver: To access this Gold Standard, several authors have proposed that in addition to treating the aetiology, future treatments for ALF should include matrisome reversal, TIMMP reduction, and MMP enhancement, allowing the stimulation of specialised macrophages in fibrosis regression, where TGFb‐1 inhibition plays a pivotal role, effects previously described by PFD in experimental liver cirrhosis by a Mexican group [10, 11, 12].