Dietary modulation of CML has been shown to influence systemic health outcomes significantly, with diets low in CML associated with lower insulin resistance, visceral fat, and oxidative stress [17] [18], whereas high-CML diets promote insulin resistance and inflammation [19] [20], largely mediated through the receptor for AGEs (RAGE) [21]-[23]. The gene discussed is AGER; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.