Neurologic comorbidities were present in 10 children with heterozygous PRRT2 variants (10/33, 30%), and movement disorders (n = 4/10, 40%) (cases 2, 13, 18, and 38) and tone abnormalities (n = 4/10, 40%) (cases 14, 15,18, and 19) were the most common comorbidities (Table 1). This evidence concerns the gene PRRT2 and movement disorder.