Similarly, among the individuals consuming cholesterol (mg/day) above the DRI, the carriers of the tripartite motif-containing protein 25 (TRIM25) rs139560285 minor allele (A) had a higher risk of T2DM than the non-carriers (OR = 2.02, p-value = 4.06 × 10−8; interaction p-value = 4.28 × 10−8). The gene discussed is TRIM25; the disease is type 2 diabetes mellitus.