The results of immunofluorescence staining confirmed the RES‐ and α‐MEL‐ and α‐MEL‐RES‐mediated effects on the regulation of β‐catenin and Wnt5a in the tumor tissues of orthotopic HS683‐Luc GB‐bearing nude mice (Figure 6D). This evidence concerns the gene WNT5A and neoplasm.