CD74 and myeloid sarcoma: Furthermore, our validation revealed the upregulation of key antigen processing and presenting genes in EAE OLCs, including Citta, CD74, Nlrc5, H2-K1, Tbp1, and H2-Aa (Fig. 3B), thereby supporting the hypothesis that OLCs, particularly Oligodendrocyte Progenitor Cells (OPCs), may function as antigen-presenting cells in MS/EAE [11, 19, 34].