We used two datasets for integration: (1) GSE106382, a dataset of induced pluripotent stem cells (iPSCs) from healthy controls, sporadic amyotrophic lateral sclerosis (ALS) and familial ALS patients including a subgroup of familial cases who carried a pathogenic mutation in the SOD1 gene (SOD1 ALS). The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.