Previously, Yu et al. [48] showed that 41 response-associated genes in 82 RA patients shared common immune pathways including type I IFN signalling, and they reported six upregulated DEGs, namely CMPK2, IFI44L, OAS3, GBP5, GBP1, IGLL5, for non-response group and 305 DEGs for response and moderate response groups. The gene discussed is IGLL5; the disease is rheumatoid arthritis.