The results of univariate logistic regression analysis of the training set (Table 2) show that: the related factors (P < 0.1) of ISR within 2 years in patients after iliac or femoral artery stent placement were diabetes, hyperlipidemia, albumin, globulin, AGR, NLR, creatinine > 81 μmol/L, hyperfibrinogenemia, below-the-knee run-offs, location of stents.Multivariate logistic regression analysis showed that the independent risk factors (P < 0.05) were diabetes, hyperlipidemia, hyperfibrinogenemia, below-the-knee run-offs, as shown in Table 3. The gene discussed is ALB; the disease is diabetes mellitus.