Specifically, right-sided colon cancers commonly show high levels of microsatellite instability (MSI), CpG island methylator phenotype (CIMP), and frequent BRAF mutations, whereas left-sided colon cancers predominantly feature chromosomal instability, alterations in APC and KRAS genes, and different methylation patterns [46, 47]. The gene discussed is APC; the disease is colonic neoplasm.