These top IBD-associated SNPs included NOD2 p.R702W (rs2066844), NOD2 p.G908R (rs2066845), NOD2 p.L1007fs (rs2066847), IL23R p.R381Q (rs11209026, protective), LRRK2 p.R1398H (rs7133914, protective), and LRRK2 p.N2081D (rs33995883). The gene discussed is NOD2; the disease is inflammatory bowel disease.