The profile of goblet cells within the epithelium was altered in individuals with asthma compared to in healthy individuals, with increased expression of CYP2F1 (cytochrome P450, a hemeprotein important for drug metabolism), MUC5B (mucin 5B, the main secreted mucin) and KLK11 and decreased expression of KRT7 and TACSTD2 (epithelial glycoprotein; Fig. 3b). This evidence concerns the gene MUC5AC and asthma.