By contrast, universal IFNα2 or bat IFNλ1-like-treatment or virus-infection of bat nasalORG (MARV), alvORG (MARV, MERS, SeV) or SIORG (SeV), resulted in minimal or no changes in the expression of these pro-inflammatory genes (Extended Data Fig. 8b,c). The gene discussed is IFNL1; the disease is viral infectious disease.