Over a thousand genes known to be associated with epilepsy have been identified but current National Health Service (NHS) epilepsy gene panel (Reference number 59, R59) includes over 600 carefully curated genes where robust scientific evidence for their pathogenicity exists—the most common mutated genes being PRRT2, SCN1A, KCNQ2 and SLC2A1 [12]. Here, PRRT2 is linked to epilepsy.