None of the three patients with SCN1A variants had a clinical diagnosis of Dravet syndrome: two were seizure-free at 12 months (one of who was diagnosed with Genetic Epilepsy with Febrile Seizures Plus (GEFS+)), while the third continued to have seizures. The gene discussed is SCN1A; the disease is encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.