Allogenic T cells from both GVHD groups showed an increased fraction of effector memory cells (CD44+CD62L−) and a decreased proportion of naive T cells (CD44−CD62L+), as compared to CD4 and CD8 T cells detected in BALB/c control groups (Figs. 8G and EV6C,D). The gene discussed is CD4; the disease is graft versus host disease.