SPI1 and neoplasm: The number of invasive and migratory tumor cells in the NC group was significantly higher than in the 125I group; the number of invasive and migratory tumor cells in the HSF1-KD + 125I group was significantly higher than in the 125I group; the number of invasive and migratory tumor cells in the HSF1-KD + 125I + PU.1-OE group was significantly lower than in the HSF1-KD + 125I group; the number of invasive and migratory tumor cells in the HSF1-KD + 125I + PU.1-OE + R406 group was significantly higher than in the HSF1-KD + 125I + PU.1-OE group.