KEGG pathway analysis revealed that DEGs were significantly enriched in the PI3K-Akt signaling pathway, Chemical carcinogenesis—DNA adducts, and MAPK signaling pathway, etc. Through correlation analysis, it was found that HSF1 is lowly expressed in cervical cancer, ROS can promote the expression of HSF1, HSF1 promotes the expression of PU.1 (SPI1), PU.1 (SPI1) promotes the expression of Dectin1 (CLEC7A), ROS promotes the expression of USP7, USP7 promotes the expression of P53, and ROS promotes the expression of BRD4 (Fig. 1). Here, HSF1 is linked to cervical carcinoma.