We further evaluated the relationship between B. parabrevis content and NK cell function and found that in comparison to the low infection group, patients in the high infection group exhibited elevated expressions of cytotoxic markers [11], including FCER1G, GZMK, IFN-γ, and TNFRSF18, heat shock protein HSPA1B [11], and the adaptive marker NKG7 [11] in tumor-infiltrating NK cells (Fig. S1I, J). This evidence concerns the gene HSPA1B and infection.