GPT and metabolic dysfunction-associated steatotic liver disease: One prime example of how genetic has been used to advance hepatology is MASLD: Understanding genetic variants associated with MASLD has allowed us to better understand the functional mechanism leading to hepatic steatosis, as these genes are often involved in hepatic lipid metabolism, oxidative stress pathways, and inflammation leading to hepatic ballooning.31, 32GWAS have promoted several genetic risk loci for MASLD by leveraging novel phenotypes including ALT proxies and magnetic resonance imaging proton density fractionated fat across various large cohorts.30