Indeed, FRC‐restricted deletion of LTβR gene in Ccl19CreLTβRfl/fl mice resulted in structural disorganization and loss of T and B cells, which led to a subpar immune response to infection (Chai et al. 2013; Cremasco et al. 2014), indicating that changes in stromal cell function directly translate into defective T cell maintenance and function. This evidence concerns the gene LTBR and infection.