Interestingly, vitamins K, D3, pantothenic acid, and biotin, which are associated with decreased common obesity (Foss, 2009), reduced inflammation (Jarvinen, et al., 2016), and increased energy expenditure and adiponectin expression (Hussein, et al., 2018), were enriched in LAF. This evidence concerns the gene ADIPOQ and obesity due to melanocortin 4 receptor deficiency.