APOA4 and chronic kidney disease: Moreover, Boes E et al. [6] reported that ApoA-IV predicts the progression of chronic kidney disease in patients with nondiabetic primary kidney disease, and Cheng CW et al. [7] and Peters KE et al. [8] presented the role of serum ApoA-IV in predicting a rapid decline in renal function in patients with type 2 DM.