Beyond its causative role in Kufs disease/CLN4, CSPα/DNAJC5 has been associated with mechanisms related to other neurodegenerative diseases such as (i) Parkinson’s disease, through the cooperation with α-synuclein as a SNARE complex chaperone (20), and (ii) as a mediator of prion-like propagation of key proteins involved in neurodegeneration such as tau, α-synuclein, and transactive response DNA binding protein 43 kDa (TDP-43) (21–25). The gene discussed is DNAJC5; the disease is neurodegenerative disease.