Notably, no single CC chemokine is a well‐recognized prognostic factor in all types of tumors, because any given chemokine has both pro‐ and anti‐cancer properties.[15] Eotaxins, including C‐C motif chemokine ligand 11 (CCL11, eotaxin‐1), CCL24 (CCL11, eotaxin‐2), and CCL26 (eotaxin‐3), are potent chemoattractants for eosinophils, which are increased in allergic diseases, such as allergic asthma, allergic rhinitis, and atopic dermatitis.[15] However, the influence of eotaxins on CRCLM and the regulation of non‐malignant cells in the TME has not been fully elucidated. This evidence concerns the gene CCL11 and allergic rhinitis.