Overexpression of CCL24 in LOVO cells resulted in a significant increase in tumor burden and decrease in survival rate of the mCRC animal model, including an increase in tumor size (Figure2A), liver weight (Figure 2B), and estimated metastasis site (Figure 2B), and decrease in OS (HR = 4.64, P = 0.002, Figure 2C). The gene discussed is CCL24; the disease is neoplasm.