ADRA2B and cancer: Given emerging evidence indicating the influence of nerves within the tumor microenvironment on cancer progression,[68, 69] we first confirmed the protein level of nerve fibers marker (antineurofilament heavy,[70] NF) in breast cancer tissue (Figure S21d, Supporting Information), subsequently examined the neuroreceptor expression level in scRNA‐seq data and discovered that C1 specifically expressed adrenergic receptors (ARs) ADRB2 and ADRA2B (Figure 5e).