We first tested if adding EE and PEG-linker would improve localizationof Pra-EE1H6 compared to that of Pra-H1 and Pra-H6 (Ac-EWPraZIKEIQRXRRA-NH2), thistime by using human cervical cancer cells (HeLa) as a cellular model.As observed before in RPE-1 cells (Figure S18B), Pra-H1 and Pra-H6 localized in a punctate pattern that partiallyoverlapped with the early endosomal marker Rab5 (Figure A,B). This evidence concerns the gene RAB5A and cervical carcinoma.