Genetic disorders with Rab10 involvement include PD, wherein hyperactivated LRRK2 increases Rab10 phosphorylation, which in turn promotes its association with Rab interacting lysosomal protein-like 1 (RILPL1), a known suppressor of ciliogenesis (Dhekne et al., 2018) and accentuates the removal of ciliary membrane proteins (Schaub and Stearns, 2013). This evidence concerns the gene LRRK2 and Parkinson disease.