In the study by Chen et al., MSNs were surface‐conjugated with ultrasmall ceria nanocrystals (CeNCs) and iron oxide nanocrystals (IONCs) to target hyperphosphorylated tau and inhibit critical pathways of tau‐driven AD pathogenesis.[133] The MSNs were loaded with methylene blue (MB), which is an inhibitor of tau aggregation. This evidence concerns the gene MAPT and Alzheimer disease.