The outcome indicators were used to evaluate rutin’s effects on inflammatory bowel disease including body weight (7 articles), colon length (4), disease activity index (DAI) (3 articles), IL-6 (2 articles), IL-10 (2 articles), IL-1β (2 articles), TNF-α in (7 articles), MPO activity (4 articles), MDA (2 articles), mRNA iNOS (3 articles), GSH (4 articles), SOD (3 articles), and CAT (3 articles). This evidence concerns the gene IL10 and inflammatory bowel disease.