MYC and neuroblastoma: These findings are consistent with previous studies that have also reported better outcomes in nonadrenal NB cases.5, 20The explanation for this disparity is that adrenal NB is often associated with negative prognostic markers such as metastasis at diagnosis, presence of MYC-N amplification,20, 211p loss, 11q loss, 17q gain, or DNA copy number alterations.21, 22Adrenal cases predominantly manifested at a distant stage (73.1%), in contrast to nonadrenal cases (34.7%).