Functional Single Nucleotide Polymorphism (SNP)/Insertion-Deletion (InDel) mutation sites are primarily enriched in Human Papillomavirus (HPV) infection, Phosphoinositide 3-kinase (PI3K)-Akt signaling pathway, Mitogen-Activated Protein Kinase (MAPK) signaling pathway, Ras signaling pathway, Huntington disease, thermogenesis (Figure 4B). This evidence concerns the gene WNK2 and Huntington disease.