Umeda et al. (2022) reported nine pediatric AML patients with UBTF-ITD in the TARGET dataset, identified using CICERO (v1.7.0) (Tian et al. 2020) and a novel soft-clipping ratio method (Umeda et al. 2022). These cases are accessible via GDC portal and can serve as positive-control when detecting UBTF-ITD events (Supplementary Fig. S5). This evidence concerns the gene UBTF and acute myeloid leukemia.