GFPT1 and urinary bladder cancer: (19) highlighted that bladder cancer-derived sEVs carrying glutamine-fructose-6-phosphate aminotransferase 1 (GFAT1) enhance tumor angiogenesis by reprogramming glucose metabolism in endothelial cells through the hexosamine biosynthesis pathway (HBP), leading to increased O-GlcNAcylation.