In order to elucidate the potential mechanisms by which HSPH1 affects NSCLC progression, we constructed the HSPH1 protein-protein interaction network (Figure 4A) through the STRING database, and obtained the 10 highest scoring predicted chaperone proteins as HSPA8(0.998), BAG2(0.995),DNAJB1(0.990),SGTA(0.987),DNAJB4(0.967),HSPBP1(0.963),BAG1(0.954),HSPA1B(0.953),DNAJA1(0.948),HSP90AA1(0.938). The gene discussed is DNAJB4; the disease is non-small cell lung carcinoma.