Next, we infected PMs from Gabra4 WT and gabra4 CKO mice with Mtb or Mabc, and found that the levels of proinflammatory cytokines and chemokines mRNA—i.e., Il6, Ccl2, Cxcl5, and Il1b—were significantly higher in gabra4 CKO PMs at 3 and 6 h of infection (Fig. 2B for Mtb; Fig. 2C for Mabc) as compared to Gabra4 WT PMs. This evidence concerns the gene IL1B and infection.