Furthermore, targeting chemokine receptors, including CXCR1, CXCR2, and CD8 on neutrophils, as well as CXCR3 on CD8+ T cells, could prevent the recruitment of healing cells to inflamed lungs (44) and may offer a potential therapeutic strategy for COPD (45). This evidence concerns the gene CXCR2 and chronic obstructive pulmonary disease.