The kidneys of mice subjected to CLP demonstrated increased expression of AKI biomarkers, including kidney injury molecule 1 (KIM1) and neutrophil gelatinase-associated lipocalin (NGAL); however, AscA treatment for 8 d, regardless of the dose, non-significantly reduced the expression of these markers (Fig. 4C,D). Here, HAVCR1 is linked to acute kidney injury.