We observed a similar pattern with UNG positively associated with APOBEC3B, but not APOBEC3A in TCGA LUAD tumor samples (Supplementary Fig. 10b, c) as well as in multiple cancer types in TCGA based on RNA-Seq data (e.g., prostate adenocarcinoma; head and neck squamous cell carcinoma; pancreatic ductal adenocarcinoma; lymphoid neoplasm diffuse large B-cell lymphoma; lung squamous cell carcinoma; Fig. 2d). This evidence concerns the gene UNG and head and neck squamous cell carcinoma.