BRCA2 and breast cancer: In addition, the AFR population also exhibited a higher frequency of additional variants associated with breast cancer predisposition: BRCA2 (OR 2.24 [95% CI (1.31, 3.84), logistic regression p = 0.0031]) and PALB2 (OR 2.92 [95% CI (2.04, 4.19), logistic regression p = 5.8 × 10−9]).