NR4A1 and neoplasm: Patients in the AFR population also present with higher grade tumours (OR 1.88 [95% CI (1.3, 2.71), logistic regression p = 7.2 × 10−4]), with a higher incidence of hormone receptor negative (HR-) disease relative to EUR (ER- OR 2.06 [95% CI (1.29, 3.28), logistic regression p = 0.0024]; PR- OR 2.07 [95% CI (1.3, 3.29), logistic regression p = 0.002]).