STUB1 and cyclic hematopoiesis: Additionally, the way that the DeCODE30 investigators ascertained “CH” may have contributed to their finding that CH was not associated with CVD, as it is distinct from the definition of “CHIP.” CH includes clonal events with known leukemic driver gene mutations, such as CHIP and mosaic chromosomal alterations (mCAs), and clonal events without clear driver genes.