While consistent with the known VGLL3::CHD7 fusion demonstrated by this tumor, the additional partner of SAM13 has not previously been reported.17 A further 2 cases demonstrated pathognomonic fusion events: KIA1549::BRAF fusion in a pilocytic astrocytoma, and ZFTA::RELA fusion in a supratentorial ependymoma. Here, VGLL3 is linked to ependymoma.