In multivariate analyses for OS, several prognostic factors including sex (P = 0.040), CP class (P = 0.007), elevated liver function tests (P = 0.008), lesions number (P = 0.004), PVTT (P = 0.004), and BCLC stage (P < 0.001) were examined.(Table 2) Stratified tumor markers based on cut-off values of AFP (500 ng/ml) and PIVKA-II (2000 mAU/ml) were significant in log-rank test. Here, AFP is linked to neoplasm.