Another notable point is that we did not find alterations in levels of full-length proteins or fragments (Jamilloux et al., 2018; Norman et al., 2010; Sanchez-Garrido et al., 2018; Valionyte et al., 2022) of autophagy adaptor proteins such as p62, TRAF6 (Figure 3—figure supplement 3), in contrast to our immunoblot analysis of human HD brains (Berg et al., 2024). The gene discussed is SQSTM1; the disease is Huntington disease.