For instance, despite growing data suggesting that PI3K/AKT and MAPK represent targets of priority for endometriosis treatment (Bao et al., 2022), inhibitors of these pathways have been shown to be more cytotoxic to cells from eutopic endometrium than endometriosis lesions (Lavogina et al., 2019). Here, AKT1 is linked to endometriosis.