Stabilization of p53 following ∆DAPK1‐mRNA expression led to the upregulation of its classical targets, including p21, p53 upregulated modulator of apoptosis (Puma), pro‐apoptotic protein regulated by p53 (Noxa), and fas cell surface death receptor (FAS), in OVCAR‐8, OVCAR‐8 PTX (a paclitaxel‐resistant cell line), and primary cells derived from patient tumor ascites. The gene discussed is FAS; the disease is neoplasm.