Puerarin and Torin1 can significantly inhibit the progression of sepsis by regulating mitochondrial autophagy-related proteins p62, LC3B, Pink1, and Parkin, thereby reversing lipopolysaccharide-induced suppression of mitochondrial autophagy in H9C2 cardiac cells (Chang et al., 2022). The gene discussed is MAP1LC3B; the disease is Sepsis.