Furthermore, E0771 cells express the two main PS scramblases isoforms Xkr8 (caspaseactivated) and TMEM16F (stress and calcium activated), permitting molecular dissociation of the cancer cell intrinsic events, side-by-side, associated with apoptosis/efferocytosis (Xkr8) from the events associated with calcium dysregulation and PS externalization on oncogenic viable cells (TMEM16F). Here, ANO6 is linked to cancer.