In this present study, we found that TNFRSF12A was notably positively related to the infiltration of most immune cells in STAD, for instance central memory CD4 T cell, Macrophage, Regulatory T cell, T follicular helper cell, central NK cell, memory CD8 T cell, NKT cell, activated Dendritic cell, Mast cell, Neutrophils. The gene discussed is CD8A; the disease is gastric adenocarcinoma.