TNFRSF12A and gastric adenocarcinoma: In this study, we found that the TIDE score, Exclusion score, and TMB level of high TNFRSF12A expression group were all markedly higher than that of low TNFRSF12A expression group, demonstrating that STAD patients with high TNFRSF12A expression might have stronger immune escape and poorer response to immunotherapy (55).