Gas-coupled dopamine receptor D1 (DRD1) was recently identified as a fibroblast-specific target for the treatment of pulmonary fibrosis and hepatic fibrosis through selective YAP/TAZ inhibition.25 DRD1 agonists have been shown to reverse lung and liver fibrosis via the inhibition of YAP/TAZ in fibroblasts. This evidence concerns the gene DRD1 and pulmonary fibrosis.