Subsequent histological analyses, including H&E staining, Sirius Red staining, Oil Red O staining (Figure 3A), as well as IHC for fibrosis markers (α‐SMA, COL1A1) and infiltrating macrophage markers F4/80 (Figure 3B and Figure S4B, Supporting Information), demonstrated significant improvements in hepatic steatosis, inflammation, and fibrosis in the GSN‐supplemented group compared to the AAV8 empty vector group. The gene discussed is COL1A1; the disease is Hepatic steatosis.