Those studies reveal the serine–threonine kinase glycogen synthase kinase 3‐beta (GSK3β) to be a hub gene in a network highly regulated by acute EtOH in the medial prefrontal cortex (mPFC) [4, 5, 6] and coanalysis with human genome‐wide association studies identified a GSK3β‐centric network associated with risk for alcohol dependence [6]. Here, GSK3B is linked to alcohol dependence.