We also treated a panel of AML primary patient blasts (n = 12; CD34+ fraction, or total mononuclear blasts in case of CD34− AMLs; see Supplementary Table 1) with the two LDHA inhibitors for 48 h and found a reduced number of viable cells upon LDHA inhibition across samples (Fig. 1H). The gene discussed is LDHA; the disease is acute myeloid leukemia.